This enzyme belongs to the family of fucosyltransferases.nThe product of this gene catalyzes the transfer of fucose fromnGDP-fucose to N-linked type complex glycopeptides. This enzyme isndistinct from other fucosyltransferases which catalyze alpha1-2,nalpha1-3, and alpha1-4 fucose addition. The expression of this genenmay contribute to the malignancy of cancer cells and to theirninvasive and metastatic capabilities. Alternatively splicednvariants encoding different isoforms have been identified.
应用类型
WB,IHC
免疫原
This FUT8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 329-357 amino acids from the Central region of human FUT8.