This gene encodes a member of the SFRP family thatncontains a cysteine-rich domain homologous to the putativenWnt-binding site of Frizzled proteins. SFRPs act as solublenmodulators of Wnt signaling. Methylation of this gene is anpotential marker for the presence of colorectal cancer. [providednby RefSeq].
应用类型
WB
免疫原
This SFRP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 263-292 amino acids from the C-terminal region of human SFRP2.