The protein encoded by this gene is a member of thentransmembrane 4 superfamily, also known as the tetraspanin family.nMost of these members are cell-surface proteins that arencharacterized by the presence of four hydrophobic domains. Thenproteins mediate signal transduction events that play a role in thenregulation of cell development, activation, growth and motility.nThis encoded protein is a cell surface antigen and is highlynexpressed in different carcinomas.
应用类型
WB
免疫原
This TM4SF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-45 amino acids from the N-terminal region of human TM4SF1.