N-methyl-D-aspartate (NMDA) receptors are a class ofnionotropic glutamate-gated ion channels. These receptors have beennshown to be involved in long-term potentiation, annactivity-dependent increase in the efficiency of synapticntransmission thought to underlie certain kinds of memory andnlearning. NMDA receptor channels are heteromers composed of the keynreceptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2nsubunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) andnNMDAR2D (GRIN2D). Alternatively spliced transcript variantsnencoding different isoforms have been found for this gene.
应用类型
WB
免疫原
This GRIN2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1291-1318 amino acids from the C-terminal region of human GRIN2A.
