Histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation.
应用类型
WB
免疫原
This KDM6B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 167-195 amino acids from the N-terminal region of human KDM6B.
