PAX7 is a member of the paired box (PAX) family ofntranscription factors. Members of this gene family typicallyncontain a paired box domain, an octapeptide, and a paired-typenhomeodomain. These genes play critical roles during fetalndevelopment and cancer growth. The specific function of the pairednbox 7 gene is unknown but speculated to involve tumor suppressionnsince fusion of this gene with a forkhead domain family member hasnbeen associated with alveolar rhabdomyosarcoma. Three transcriptnvariants encoding different isoforms have been found for this gene.
应用类型
WB
免疫原
This PAX7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 410-437 amino acids from the C-terminal region of human PAX7.