Phosphatidylcholine (PC)-specific phospholipases D (PLDs;nEC 3.1.4.4) catalyze the hydrolysis of PC to produce phosphatidicnacid and choline. Activation of PC-specific PLDs occurs as anconsequence of agonist stimulation of both tyrosine kinase and Gnprotein-coupled receptors. PC-specific PLDs have been proposed tonfunction in regulated secretion, cytoskeletal reorganization,ntranscriptional regulation, and cell cycle control.[supplied bynOMIM].
应用类型
WB
免疫原
This PLD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-39 amino acids from the N-terminal region of human PLD2.
