This gene represents a nuclear retinoic acid receptor. Thenencoded protein, retinoic acid receptor alpha, regulatesntranscription in a ligand-dependent manner. This gene has beennimplicated in regulation of development, differentiation,napoptosis, granulopoeisis, and transcription of clock genes.nTranslocations between this locus and several other loci have beennassociated with acute promyelocytic leukemia. Alternatively splicedntranscript variants have been found for this locus.
应用类型
WB,IHC,ICC
免疫原
This RARA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-349 amino acids from the C-terminal region of human RARA.
