May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 239 and 872, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D (By similarity). Essential factor for the specific interaction between FGF23 and FGFR1 (By similarity).
应用类型
WB,FCM
免疫原
This KL antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 331-365 amino acids from the Central region of human KL.
