Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down- regulation of EGF receptor.
应用类型
WB,ICC,FCM
免疫原
This FAM125A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 16-50 amino acids from human FAM125A.
