Component of the Integrator complex. The Integrator complex is involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes.
应用类型
WB,FCM
免疫原
This INTS3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 518-551 amino acids from the Central region of human INTS3.