Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down- regulation of EGF receptor.
应用类型
WB
免疫原
This FAM125A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 152-186 amino acids from the Central region of human FAM125A.
