Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death.
应用类型
WB
免疫原
This SH3BP5 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 63-97 amino acids from human SH3BP5.