Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity.
应用类型
WB
免疫原
This Natriuretic Peptide Receptor C antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 200-420 amino acids from the human region of human Natriuretic Peptide Receptor C.