Anchors cAMP-dependent protein kinase (PKA) and acts as an adapter protein to selectively couple G alpha-13 and Rho. Augments gene activation by the estrogen receptor in an element- specific and ligand-dependent manner. Activates estrogen receptor beta by a p38 MAPK-dependent pathway. Stimulates exchange activity on Rho proteins in vitro, but not on CDC42, Ras or Rac and may bind calcium ions.
应用类型
WB
免疫原
This AKAP13 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 18-170 amino acids from human AKAP13.
