Involved in pre-mRNA splicing as component of the U4/U6- U5 tri-snRNP complex, one of the building blocks of the spliceosome. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation.
应用类型
WB
免疫原
This PRPF6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 196-229 amino acids from the N-terminal region of human PRPF6.
