The low density lipoprotein receptor (LDLR) gene familynconsists of cell surface proteins involved in receptor-mediatednendocytosis of specific ligands. This gene encodes a lipoproteinnreceptor that is a member of the LDLR family and plays importantnroles in VLDL-triglyceride metabolism and the reelin signalingnpathway. Mutations in this gene cause VLDLR-associated cerebellarnhypoplasia. Alternative splicing generates multiple transcriptnvariants encoding distinct isoforms for this gene. [provided bynRefSeq].
应用类型
WB,IHC
免疫原
This VLDLR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 484-510 amino acids from the Central region of human VLDLR.
