The protein encoded by this gene interacts withnmicrotubules and is functionally associated with beta-amyloidnprecursor protein transport and/or processing. The beta-amyloidnprecursor protein is a cell surface protein with signal-transducingnproperties, and it is thought to play a role in the pathogenesis ofnAlzheimer's disease. This gene has been found to be highlynexpressed in breast cancer. Multiple polyadenylation sites havenbeen found for this gene.
应用类型
WB
免疫原
This APPBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-271 amino acids from the Central region of human APPBP2.