The protein encoded by this gene catalyzes thenisomerization of mannose 6-phosphate to mannose 1-phosphate, whichnis a precursor to GDP-mannose necessary for the synthesis ofndolichol-P-oligosaccharides. Mutations in this gene have been shownnto cause defects in glycoprotein biosynthesis, which manifests asncarbohydrate-deficient glycoprotein syndrome type I. [provided bynRefSeq].
应用类型
WB
免疫原
This PMM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-226 amino acids from the C-terminal region of human PMM2.
