This gene belongs to the forkhead family of transcriptionnfactors which are characterized by a distinct forkhead domain. Thisngene likely functions as a trigger for apoptosis through expressionnof genes necessary for cell death. Translocation of this gene withnthe MLL gene is associated with secondary acute leukemia.nAlternatively spliced transcript variants encoding the same proteinnhave been observed.
应用类型
WB,IHC
免疫原
This FOXO3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human FOXO3.
