MAFF is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. This protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription.
应用类型
WB,IHC,FCM
免疫原
This MAFF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-92 amino acids from the Central region of human MAFF.
