Cooperates with AGTR2 to inhibit ERK2 activation and cell proliferation. May be required for AGTR2 cell surface expression. Together with PTPN6, induces UBE2V2 expression upon angiotensin-II stimulation. Isoform 1 inhibits breast cancer cell proliferation, delays the progression of mitosis by prolonging metaphase and reduces tumor growth.
应用类型
WB
免疫原
This MTUS1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 983-1017 amino acids from human MTUS1.
