May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. Binds CTNNB1 and may thereby act as an inhibitor of the Wnt signaling pathway. Competes with LIN7A for KCNJ4 binding, and thereby promotes KCNJ4 internalization. May play a role in the Rho signaling pathway. May play a role in activation of CDC42 by the viral protein HPV16 E6.
应用类型
WB
免疫原
This TAX1BP3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 71-103 amino acids from human TAX1BP3.
