The protein encoded by this gene contains a RING fingerndomain, a motif present in a variety of functionally distinctnproteins and known to be involved in protein-protein andnprotein-DNA interactions. This gene is located in a chromosomalnregion known to be frequently deleted in patients withnneurofibromatosis. Alternatively spliced transcript variantsnencoding distinct isoforms have been reported. [provided bynRefSeq].
应用类型
WB
免疫原
This RNF135 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 375-401 amino acids from the C-terminal region of human RNF135.