This gene contains 37 exons, spans approximately 59-kb,nand is located in the 3p22-p21.3 chromosomal segment that isncommonly deleted in various carcinomas. Several alternativelynspliced transcripts have been observed that contain disruptedncoding regions and likely encode nonfunctional proteins. Aberrantntranscription of this gene may be involved in carcinogenesis of thenlung, esophagus, and kidney.
应用类型
WB
免疫原
This DLEC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 879-908 amino acids from the Central region of human DLEC1.