Excision repair cross-complementing rodent repairndeficiency, complementation group 5 (xeroderma pigmentosum,ncomplementation group G) is involved in excision repair ofnUV-induced DNA damage. Mutations cause Cockayne syndrome, which isncharacterized by severe growth defects, mental retardation, andncachexia. Multiple alternatively spliced transcript variantsnencoding distinct isoforms have been described, but the biologicalnvalidity of all variants has not been determined. [provided bynRefSeq].
应用类型
WB
免疫原
This ERCC5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1151-1178 amino acids from the C-terminal region of human ERCC5.
