Elastases form a subfamily of serine proteases thatnhydrolyze many proteins in addition to elastin. Humans have sixnelastase genes which encode the structurally similar proteinsnelastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases,npancreatic elastase 1 is not expressed in the pancreas. To date,nelastase 1 expression has only been detected in skin keratinocytes.nClinical literature that describes human elastase 1 activity in thenpancreas or fecal material is actually referring tonchymotrypsin-like elastase family, member 3B.
应用类型
WB
免疫原
This CELA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-79 amino acids from the N-terminal region of human CELA1.