The protein encoded by this gene is a member of the RAMPnfamily of single-transmembrane-domain proteins, called receptorn(calcitonin) activity modifying proteins (RAMPs). RAMPs are type Intransmembrane proteins with an extracellular N terminus and ancytoplasmic C terminus. RAMPs are required to transportncalcitonin-receptor-like receptor (CRLR) to the plasma membrane.nCRLR, a receptor with seven transmembrane domains, can function asneither a calcitonin-gene-related peptide (CGRP) receptor or annadrenomedullin receptor, depending on which members of the RAMPnfamily are expressed. In the presence of this (RAMP3) protein, CRLRnfunctions as an adrenomedullin receptor.
应用类型
WB
免疫原
This RAMP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-118 amino acids from the C-terminal region of human RAMP3.
