Cytochrome c oxidase (COX), the terminal component of thenmitochondrial respiratory chain, catalyzes the electron transfernfrom reduced cytochrome c to oxygen. This component is anheteromeric complex consisting of 3 catalytic subunits encoded bynmitochondrial genes and multiple structural subunits encoded bynnuclear genes. The mitochondrially-encoded subunits function innelectron transfer, and the nuclear-encoded subunits may function innthe regulation and assembly of the complex. This nuclear genenencodes polypeptide 1 (muscle isoform) of subunit VIIa and thenpolypeptide 1 is present only in muscle tissues. Other polypeptidesnof subunit VIIa are present in both muscle and nonmuscle tissues,nand are encoded by different genes.
应用类型
WB
免疫原
This COX7A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-38 amino acids from the Central region of human COX7A1.
