Histones are basic nuclear proteins that are responsiblenfor the nucleosome structure of the chromosomal fiber inneukaryotes. Nucleosomes consist of approximately 146 bp of DNAnwrapped around a histone octamer composed of pairs of each of thenfour core histones (H2A, H2B, H3, and H4). The chromatin fiber isnfurther compacted through the interaction of a linker histone, H1,nwith the DNA between the nucleosomes to form higher order chromatinnstructures. This gene encodes a member of the histone H1 family.
应用类型
WB
免疫原
This H1FX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-167 amino acids from the C-terminal region of human H1FX.
