The protein encoded by this gene mediates transcriptionalncontrol by interaction with the Kruppel-associated box repressionndomain found in many transcription factors. The protein localizesnto the nucleus and is thought to associate with specific chromatinnregions. The protein is a member of the tripartite motif family.nThis tripartite motif includes three zinc-binding domains, a RING,na B-box type 1 and a B-box type 2, and a coiled-coil region.
应用类型
WB,IHC,ICC
免疫原
This TRIM28 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-207 amino acids from the N-terminal region of human TRIM28.