The protein encoded by this gene binds to annanti-proliferative protein, B-cell translocation protein 1, whichnnegatively regulates cell proliferation. Binding of the twonproteins, which is driven by phosphorylation of thenanti-proliferative protein, causes signaling events in cellndivision that lead to changes in cell proliferation associated withncell-cell contact. The protein has both mouse and yeast orthologs.nAlternate splicing of this gene results in two transcript variantsnencoding different isoforms.
应用类型
WB,IHC,ICC
免疫原
This CAF-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 34-61 amino acids from the N-terminal region of human CAF-1.
