Receptor for SLIT1 and SLIT2 which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex. May be required for lung development.
应用类型
WB
免疫原
This ROBO1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1097-1130 amino acids from human ROBO1.
