This nuclear gene encodes a mitochondrial protein whichnbelongs to FRATAXIN family. The protein functions in regulatingnmitochondrial iron transport and respiration. The expansion ofnintronic trinucleotide repeat GAA results in Friedreich ataxia.nAlternative splicing results in multiple transcript variants.
应用类型
WB
免疫原
This FXN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-64 amino acids from the N-terminal region of human FXN.
