This gene product belongs to the claudin protein familynwhose members have been identified as major integral membranenproteins localized exclusively at tight junctions. Claudins arenexpressed in an organ-specific manner and regulate tissue-specificnphysiologic properties of tight junctions. This protein isnexpressed in the intestine. Alternatively spliced transcriptnvariants with different 5' untranslated region have been found fornthis gene.
应用类型
WB,IHC,FCM
免疫原
This CLDN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 200-227 amino acids from the C-terminal region of human CLDN2.
