This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
应用类型
WB,IHC,ICC
免疫原
This GFAP monoclonal antibody is generated from mouse immunized with GFAP recombinant protein.
