May play a critical role in death receptor-induced apoptosis and may target CASP8 and CASP10 to the nucleus. May regulate degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3.
应用类型
WB
免疫原
This DEDD2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 43-75 amino acids from human DEDD2.
