ATPase required for FANCD2 ubiquitination, a key reaction in DNA repair. Binds to ssDNA but not to dsDNA. Recruited to forks stalled by DNA interstrand cross-links, and required for cellular resistance to such lesions.
应用类型
WB
免疫原
This FANCM antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1752-1783 amino acids from human FANCM.
