Probable catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Amplification-dependent oncogene; promotes cell proliferation and tumorigenesis by down- regulating expression of the tumor suppressor protein, PML. May play a role in the pathogenesis of the lung cancer development and progression.
应用类型
WB
免疫原
This CSNK2A3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 296-330 amino acids from human CSNK2A3.
