Plays a role in DNA repair through recruitment of the FA core complex to damaged DNA. Regulates FANCD2 monoubiquitination upon DNA damage. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed. Targets FANCM/FAAP24 complex to the DNA, preferentially to single strand DNA.
应用类型
WB
免疫原
This FAAP24 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1-32 amino acids from human FAAP24.
