Transcriptional activator that directly regulates early activation of the myogenic determination gene MYF5 by binding in a sequence-specific manner to the early epaxial enhancer element of it. Involved in somitogenesis during embryogenesis and somite development and differentiation into sclerotome and dermomyotome. Required for the initiation and/or maintenance of proper organization of the sclerotome, dermomyotome and myotome (By similarity).
应用类型
WB
免疫原
This DMRT2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 222-256 amino acids from human DMRT2.
