Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species. Enhances the stability of mRNA coding for BCL2. NADPH binding interferes with mRNA binding.
应用类型
WB
免疫原
This CRYZ antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 248-282 amino acids from the C-terminal region of human CRYZ.