Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation (By similarity). Enhances fibroblast growth factor-induced angiogenesis (in vitro).
应用类型
WB
免疫原
This JAG1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1190-1224 amino acids from the C-terminal region of human JAG1.