Acts as a transcriptional activator by binding to an A/T-rich sequence, the FLAT element, in the insulin gene promoter. Required for development of the roof plate and, in turn, for specification of dorsal cell fates in the CNS and developing vertebrae (By similarity).
应用类型
WB
免疫原
This LMX1A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 303-337 amino acids from the C-terminal region of human LMX1A.
