Assembly protein recruiting clathrin and adapter protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. May be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. Involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction.
应用类型
WB
免疫原
This PICALM antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 385-415 amino acids from the Central region of human PICALM.
