This gene encodes the D2 subtype of the dopamine receptor.nThis G-protein coupled receptor inhibits adenylyl cyclase activity.nA missense mutation in this gene causes myoclonus dystonia; othernmutations have been associated with schizophrenia. Alternativensplicing of this gene results in two transcript variants encodingndifferent isoforms. A third variant has been described, but it hasnnot been determined whether this form is normal or due to aberrantnsplicing.
应用类型
WB
免疫原
This DRD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 307-336 amino acids from the C-terminal region of human DRD2.
