Histones are basic nuclear proteins that are responsiblenfor the nucleosome structure of the chromosomal fiber inneukaryotes. Two molecules of each of the four core histones (H2A,nH2B, H3, and H4) form an octamer, around which approximately 146 bpnof DNA is wrapped in repeating units, called nucleosomes. Thenlinker histone, H1, interacts with linker DNA between nucleosomesnand functions in the compaction of chromatin into higher ordernstructures. This gene is intronless and encodes a member of thenhistone H2B family. Transcripts from this gene lack polyA tails butninstead contain a palindromic termination element. This gene isnfound in the large histone gene cluster on chromosome 6. [providednby RefSeq].
应用类型
WB
免疫原
This HIST1H2BG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HIST1H2BG.
