Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.
应用类型
WB
免疫原
This ASGR2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 21-54 amino acids from the N-terminal region of human ASGR2.
