Regulates the proliferation and differentiation of hematopoietic cells. Overexpression block the TPA-induced megakaryocytic differentiation in the K562 cell model. May also prevent cell apoptosis through the activation of the nuclear factor-kappa B (NF-kB).
应用类型
WB
免疫原
This HEMGN antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 355-389 amino acids from the C-terminal region of human HEMGN.