Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide. Seems to be exclusively coupled to the G(q) subclass of heteromeric G proteins, which activates the phospholipase C mediated signaling cascade (By similarity).
应用类型
WB
免疫原
This HCRTR1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 256-291 amino acids from the Central region of human HCRTR1.
